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br Indigenous communities experience some of the highest rat
2019-05-10
Indigenous communities experience some of the highest rates of suicide globally, especially among young people. This worrying epidemic has already been shown in Inuit communities of North America and Greenland and the Amazonian groups of Guyana, but recently has been shown to extend to Australian
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br Case report A year old man
2019-05-10
Case report A 67-year-old man with a past history of hepatitis B carrier presented with body weight loss of 10 kg, general weakness and abdominal fullness for three months and was admitted for the impression of decompensated liver cirrhosis. Physical examination of the patient revealed a diffuse
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This is similar to the z score with
2019-05-09
This is similar to the z score, with the mean intra-sample correlation providing a “population mean”. A score greater than −1 was considered a good match (1 point), a score greater than −2 was a partial match (0.5 points), and a score less than −2 was no match (0 points). Spatial resolution was then
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Regarding patients with a lower annual risk of thromboemboli
2019-05-09
Regarding patients with a lower annual risk of thromboembolism ( Management of direct acting oral anticoagulants during pacemaker insertion There are less data available regarding management of DOACs peri-procedurally. The general principle is that PM/ICD implantation is considered a low bleeding
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It is noteworthy that in a recent study Le Scouarnec
2019-05-09
It is noteworthy that in a recent study, Le Scouarnec et al. [199]. estimated the burden of rare coding variation in arrhythmia susceptibility genes among 167 BrS index patients and compared that with 167 individuals ≥65 years old with no history of cardiac arrhythmia. The authors concluded that, ex
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Economic sanctions have exacerbated the brutality of
2019-05-09
Economic sanctions have exacerbated the brutality of this conflict many-fold, removing any prospects for peace and reconciliation. We need some reality to gauge their manifold effects before Syria descends into another Iraq, the devastating health consequences of which were well documented. Syria u
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Delays in diagnosis due to
2019-05-09
Delays in diagnosis due to the subtlety and focal nature of the intravascular infiltrates often lead to a terminal disease with death before chemotherapy is initiated. R-CHOP plus CNS prophylaxis is the treatment of choice in patients [30,31] without 7 8-dihydroxyflavone involvement. CNS involvement
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br In its July editorial drew attention
2019-05-09
In its July editorial, drew attention to the ethical challenges posed by the Zika enba cost outbreak. The Regional Program on Bioethics at the Pan American Health Organization (PAHO) arranged an ethics consultation, funded by the Wellcome Trust, to provide ethically sound guidance for the outbreak
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First Speakman and colleagues do not mention the development
2019-05-09
First, Speakman and colleagues do not mention the developments in the 2000s, when notable EU attention was given to global health. In 2010, there was a high-level conference and the launch of a European Commission Communication, which stated that the EU\'s commitment to global health should mainly f
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We used MRI images taken to weeks after a crisis
2019-05-09
We used MRI images taken 1 to 8 weeks after a crisis to explore basal ganglion involvement and found restricted UNC 0642 at the basal ganglion. This finding suggests that cytotoxic damage to the basal ganglion persists post-crisis. When MRI images were obtained much longer after crisis, restricted
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Cardiac fibroblasts express various ion channels in particul
2019-05-09
Cardiac fibroblasts express various ion channels, in particular voltage-gated K cftr and nonselective cation channels of the transient receptor potential (TRP) family . Both K and TRP channels are important determinants of fibroblast function, with TRP channels acting as Ca entry pathways that stim
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Based on the methodology used in
2019-05-09
Based on the methodology used in previous studies, the EGM source for the Wavelet algorithm has been nominally programmed as the Can-RV coil EGM [13]. As the nominal EGM source includes the generator, myopotentials induced due to body motion or other muscle activity are likely to influence the arrhy
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tazarotene br Results br Discussion We identified
2019-05-09
Results Discussion We identified a novel, heterozygous nonsense SCN5A mutation, Q779X, in a family with overlapped phenotype with progressive conduction defects and BrS. The proband suffered from SSS at the age of three, and subsequent ventricular fibrillation with a coved type Brugada ECG pat
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The miR signature of exosomes
2019-05-08
The miR signature of exosomes isolated from bulk prostate cancer thip (Fig. 1A, blue cells) and from their cancer stem cell compartment (Fig. 1A, green cells), display high levels of miR-21, miR-30 and miR-218 [23] (Fig. 1A, blue arrow). miR-21 and miR-30 have been identified as key regulators of o
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br Interpretation of identified genetic variants and genetic
2019-05-08
Interpretation of identified genetic variants and genetic counseling Although the current expert consensus statement recommends that comprehensive or BrS1 (SCN5A) targeted BrS genetic testing can be useful for genetic testing [63], not all the published SCN5A mutations in BrS have been subjected
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